The Gerdts Lab

University of California, San Francisco

Selected Publications

 

  1. Bodansky, A., Ahyong, V., Dayao, M., Asaki, J., Vanasupa, S., Dandekar, R., Chen, S., Sabatino, J., Klauer, S., Knudsen, G., Lizama Valenzuela, C., McCutcheon, K., Zorn, K., Sidhu, S., Yu, D., Garcia, S., Quandt, Z., Wang, C.-Y., Castillo Rojas, B., Tilton, I., Citron, Y.R., Sharathchandra, A., Gerungan, C., Tomko, S., Robbins, N.M., McKeon, A., Cooper, T., Harms, M., Gomez, R., Fancy, S.P.J., Green, A.J., Caliskan, I., Cadwell, C.R., Ostrem, B.E.L., Karalius, M., Braun, L., Gupta, S., Francisco, C., Peng, G., Reddy, A.T., Nash, K., Pleasure, S.J., Mandel-Brehm, C., Arnold, T.D., Consortium, Anderson, M.S.*, Gerdts, J.*, Wilson, M.R.*, DeRisi, J.L.*, 2026. AEGIS reveals epitope- and clone-resolved convergence of CNS B and T cell autoreactivity in ROHHAD. bioRxiv.
     

  2. Hayashi, F., Mittl, K., Dandekar, R., Gerdts, J., Hassan, E., Schubert, R.D., Oshiro, L., Loudermilk, R., Greenfield, A., Augusto, D.G., Havton, G., Anumarlu, S., Surapaneni, A., Ramesh, A., Tran, E., Koshal, K., Kizer, K., Dreux, J., Cagalingan, A.K., Schustek, F., Flood, L., Moore, T., Kirkemo, L.L., Fisher, I.J., Cooper, T., Harms, M., Gomez, R., University of California, San Francisco MS-EPIC Team, Clelland, C.D., Sibener, L., Cree, B.A.C., Hauser, S.L., Hollenbach, J.A., Gee, M., Wilson, M.R., Zamvil, S.S., Sabatino, J.J., Jr, 2026. Antigen specificity of clonally enriched CD8+ T cells in multiple sclerosis. Nat. Immunol. 1–13.

  1. Gupta, S., Martinov, T., Thelen, A., Sunahara, M., Mureli, S., Vazquez, A., Gerdts, J., Dandekar, R., Cortese, I., Fouassier, C., Schanzer, E., Urnov, F.D., Marson, A., Shy, B.R., Greenberg, P.D., Wilson, M.R., 2024. Antigen-specific T cell receptor discovery for treating progressive multifocal leukoencephalopathy. bioRxiv

  1. Stevens, A.J., Harris, A.R., Gerdts, J., Kim, K.H., Trentesaux, C., Ramirez, J.T., McKeithan, W.L., Fattahi, F., Klein, O.D., Fletcher, D.A., Lim, W.A., 2023. Programming multicellular assembly with synthetic cell adhesion molecules. Nature 614, 144–152. 

  1. Gerdts, J., Brace, E.J., Sasaki, Y., DiAntonio, A., Milbrandt, J., 2015. SARM1 activation triggers axon degeneration locally via NAD+ destruction. Science.

  1. Gerdts, J., Summers, D.W., Milbrandt, J., DiAntonio, A., 2016. Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism. Neuron 89, 449–460.

  1. Gerdts, J., Summers, D.W., Sasaki, Y., DiAntonio, A., Milbrandt, J., 2013. Sarm1-mediated axon degeneration requires both SAM and TIR interactions. J. Neurosci. 33, 13569–13580.

  1. Gerdts, J., Sasaki, Y., Vohra, B., Marasa, J., Milbrandt, J., 2011. Image-based screening identifies novel roles for IkappaB kinase and glycogen synthase kinase 3 in axonal degeneration. J. Biol. Chem. 286, 28011–28018.

  1. Bhattacharya, M.R.C., Gerdts, J., Naylor, S.A., Royse, E.X., Ebstein, S.Y., Sasaki, Y., Milbrandt, J., DiAntonio, A., 2012. A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degeneration. J. Neurosci. 32, 5054–5061.

  1. Kintner, D.B., Luo, J., Gerdts, J., Ballard, A.J., Shull, G.E., 2006. Na+-K+-Cl-cotransport and Na+/Ca2+ exchange in astrocyte mitochondrial dysfunction in response to in vitro ischemia. J. Neurosci.